
FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.

Samuel L. Jackson

Julianna Margulies

Nathan Phillips

Kenan Thompson

Rachel Blanchard

Flex Alexander

Keith Dallas

Sunny Mabrey

Lin Shaye

Elsa Pataky

Casey Dubois

Gerard Plunkett

Terry Chen

Emily Holmes

Mark Houghton

David Koechner

Bobby Cannavale

Yan-Kay Crystal Lowe

Todd Louiso

Kendall Cross

Samantha McLeod

Taylor Kitsch

Kevin McNulty

Agam Darshi

Lisa Marie Caruk

Mi-Jung Lee

Lesley Aletter

Byron Lawson

Tom Butler
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